AEMCA Practice Exam

What is a common selective beta-1 adrenergic agonist used for treating cardiogenic shock?

1. Albuterol

2. Dopamine

3. Dobutamine

4. Epinephrine

The correct answer is: Dobutamine

Dobutamine is a common selective beta-1 adrenergic agonist that is used primarily in the treatment of cardiogenic shock. This medication specifically targets beta-1 receptors in the heart, leading to an increase in heart rate and myocardial contractility. These effects are particularly beneficial in patients experiencing cardiogenic shock, as they help to improve cardiac output and perfusion to vital organs. When the heart is unable to pump effectively, as seen in cardiogenic shock, enhancing cardiac contractility is a critical therapeutic goal. Dobutamine’s selective action minimizes effects on the heart’s beta-2 and alpha receptors, allowing for improved cardiac output with potentially fewer unwanted side effects compared to less selective agonists. In contrast, medications like epinephrine are non-selective and affect both beta-1 and beta-2 receptors, which may lead to unwanted vasodilation or increased heart rates that could exacerbate certain conditions. Dopamine, while it can provide positive inotropic effects, is not as specifically targeted for beta-1 adrenergic stimulation in the context of cardiogenic shock compared to dobutamine. Lastly, albuterol is primarily a beta-2 agonist used mainly for asthma and does not play a significant role in the treatment of cardi